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Re-use of inferred parent names in large families #119

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Awtum opened this issue Aug 9, 2023 · 1 comment
Open

Re-use of inferred parent names in large families #119

Awtum opened this issue Aug 9, 2023 · 1 comment

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@Awtum
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Awtum commented Aug 9, 2023

In cases of large families (in this case merged from many smaller families during infer), inferred parents between sets of siblings appear to be re-used. This gives the appearance of many children of the same parents, when in reality it is multiple sets of siblings consisting of 2 or 3 each that may be distantly related.

@brentp
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brentp commented Aug 22, 2023

Yes, --infer tries to do simple things to do the best it can, but in low-quality or low-coverage samples, it can make many mistakes.

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