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Description:
Integrate annotations from cancer-specific databases such as OncoKB, CIViC, My Cancer Genome, and Cancer Hotspots. These databases provide valuable cancer-related variant information that can enhance the utility of the annotated VCF files, particularly for cancer research projects.
Tasks:
Update Configuration File:
Add paths for the new cancer-specific VCF annotation files in config.yaml.
Define fields for each new VCF annotation in the configuration file.
Utilize Existing Snakemake Rule:
Use the generalized rule for annotating with VCF files from Feature request: Generalize annotation script to annotate arbitrary VCF file data #4.
Generate required VCF files for OncoKB, CIViC, My Cancer Genome, and Cancer Hotspots annotations.
Documentation:
Update the README to include new configuration options and usage instructions for cancer-specific annotations.
Document the new rules and their purpose within the script.
Additional Context:
Adding these cancer-specific annotations will improve the utility of the VCF files for cancer research by providing comprehensive and relevant variant information.
The text was updated successfully, but these errors were encountered:
Description:
Integrate annotations from cancer-specific databases such as OncoKB, CIViC, My Cancer Genome, and Cancer Hotspots. These databases provide valuable cancer-related variant information that can enhance the utility of the annotated VCF files, particularly for cancer research projects.
Tasks:
Update Configuration File:
config.yaml
.Utilize Existing Snakemake Rule:
Feature request: Generalize annotation script to annotate arbitrary VCF file data #4
.Documentation:
Additional Context:
Adding these cancer-specific annotations will improve the utility of the VCF files for cancer research by providing comprehensive and relevant variant information.
The text was updated successfully, but these errors were encountered: